However, due to differences in the physiological traits and gene expression between mice and humans, mouse models cannot replicate the symptoms or pathology of human diseases in some cases [ 1].
While this model cannot precisely replicate the epidemiological situation in any given location, it applies a standardized methodology across a wide range of settings, thereby illustrating important interactions between epidemiological parameters and projected impact.
On the other hand, some aspects of the German model cannot be easily replicated elsewhere.
Thus, current cellular DPR models cannot fully replicate the pattern of intranuclear aggregates found in patient tissue.
These forms can be considered simplified and partial models of T2DM, although, they cannot replicate the complexity of its pathogenesis.
First, in several cases the model fits the control group but cannot replicate the impact of the program.
The interest stems from a growing concern that animal models and simple 2D culture systems cannot replicate essential features of human physiology that are crucial to predict drug response, or simply to develop new therapeutic strategies to repair or replace damaged organs.
As it has been reported elsewhere, an nth order model is described by a mathematical function that cannot replicate the initial induction period typical of the function describing a chain scission model [10].
At 5 feet 9 inches and 150 pounds, Len does not imagine himself playing in the N.B.A. or even the N.C.A.A. tournament; he matches his local role model, Nate Robinson of the Knicks, in height and hustle but, alas, cannot replicate his remarkable 43 ½-inch vertical leap.
While the carotid ligation model is advantageous in providing a discrete, macrophage-rich vascular lesion, it cannot replicate the complex, chronic plaques that develop in humans.
