Across in vivo models, the top candidates showed highly concordant responses at 1 and 3 days post-injury, which highlights the predictive power of our analysis strategies and the possible biological relevance of these genes.
Here, we show that across in vivo models, a set of top candidates showed highly concordant responses at 1 and 3 days post-injury (dpi).
Many vaccine candidates shown to be effective in murine models have subsequently failed to pass the test in guinea pig models.
Other candidate show up just fine.
To challenge a critical qualitative property, we tested which of the model candidates did or did not show perfect adaptation behavior by comparing initial and steady-state simulated Hog1 activation after adaptation.
All other candidate models show differences for each coefficients between these two extreme cases.
When more than one candidate model showed explanatory ability as indicated by an AICc value that differed from the best model (i.e., the one with the smallest AICc) by ≤2, we model-averaged parameter estimates to get effect sizes and the associated variances from the 95% confidence set of candidate models (Burnham and Anderson 2002).
National outlook - The HuffPollster poll tracking model continues to show Republican candidates with advantages adding up to a 53 seat majority, although the margins in three states, Iowa, Kansas and Georgia, remain less than two percentage points and a handful of others -- Iowa, Colorado and Alaska -- only slightly better.
M. falcata is shown to be a model candidate for studying abiotic stress-responsive mechanisms in legumes.
We first complete our discussion of the candidate-voter model showing, in particular, that, in equilibrium, two candidates cannot be too far apart.
