Sentence examples for model by administering from inspiring English sources

In the present study we tried to decrease the levels of NO in our GTN headache model by administering pure oxygen in a dose, 7 l/min which has been shown to be effective in the treatment of cluster headache in a double-blind trial [8, 9] and in clinical practice [8, 10].

We next explored whether GM-CSF was critical also for joint pain development in this OA-like model by administering a neutralizing mAb to GM-CSF prophylactically.

To achieve an increase in epithelial permeability we modified the model by administering LPS continuously [ 21] instead of increasing a bolus dose.

We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal anti-inflammatory drugs (NSAIDs) with differing selectivity profiles: robenacoxib (COX-2 selective) and ketoprofen (COX-1 selective).

Here, we have examined the function of TIM-2 in the development of collagen-induced arthritis (CIA), which is a Th1-mediated autoimmune disease model, by administering a newly generated anti-TIM-2 monoclonal antibodies (mAbs).

LPS injury was performed as a two-hit model by administering a single bolus of 1 mg/kg body weight intraperitoneally 24 hours prior to the experiment, followed by a constant intravenous infusion of LPS (1 mg/kg/hr) during the 6-hour experimental period.

Type-1 diabetes is an autoimmune disease that destroys insulin-producing pancreatic β-cells, which we modeled by administering the β-cell toxin STZ (Sigma S0130) to mice at 8 weeks of age fed a ND (ND+STZ; Arora et al., 2009; Gilbert et al., 2011).

When Indian RYR was evaluated in rat models by administering RYR at doses of 1.2 mg/kg and 2.4 mg/kg/day to the rats for 30 days, the extract at both doses could maintain the lipid profile (TC, TG, HDL, LDL-C and VLDL-C) of the rats at near normal status [ 30].

This model may be improved, for example, by administering antimicrobial drugs or creating transgenic mice.

Secondly, we constructed an artificial short-term model of hypoxemia by administering a hypoxic gas mixture.

We modelled this synergism by administering a sublethal dose of influenza virus that caused a mild transient pulmonary infection without systemic disease followed by bacterial challenge that is not lethal without prior viral infection (McCullers & Rehg, 2002).