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As shown in Table 4, and consistent with known demographic differences between the Marin County and other urban US-wide SEER populations [35], [36], Marin's cases and controls are balanced with regard to the shown risk characteristics but are significantly older and have later ages at first birth than that of the model building cases and controls.
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We randomly partitioned our dataset into a training set for model building (733 cases, 748 controls) and a test set for model assessment (765 cases, 747 controls).
DSM has six stages, namely i) problem statement and preliminary data collection; ii) field studies; iii) model building; iv) case study and empirical exploration; v) simulation; and vi) policy analysis.
To build and assess a PD estimation model, we randomly partitioned the dataset, consisting of information on 2,993 women, into two parts: a training set for model building (733 breast cancer cases and 748 healthy controls), and a test set for model assessment (765 cases and 747 controls).
Data from the training cohort was split into a fraction for model building and model evaluation (10 cases and 10 controls).
All MD simulations were carried out using version 4.04 of the Groningen machine for chemical simulations (GROMACS) (Hess et al. 2008) or assisted model building with energy refinement (AMBER 12 (Case et al. 2005) software packages.
Model building methods are application oriented, varying from case to case.
This paper describes the proposed participatory model building (PMB) framework and provides a case study of its application in Québec, Canada.
Most model building in biology involves either special case analytical models or simulation models.
Inquiry type: guided inquiry, open-ended inquiry, research (including teacher-collaborative and structured research experiences), and other (e.g., case studies, problem-based learning, model building).
This can be explained by the relative scarcity of such cases and the regularity of the covariance model building process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com