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Our goals were to design a novel meso-scale model bridging the gap between microfluidic and macro-scale studies, and high-throughput screen the effects of multiple variables on the vascularization of bone-mimicking tissues.
This manuscript describes a modeling workflow based on a new Rhinoceros-based plugin that combines an Urban Building Energy Model with a network topology optimization and a heat generation scenario model bridging the gap between the planning phase and the design phase.
We thus offer a model bridging the two processes.
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When you've gotten to your ideal looks like and works like models, bridging the two becomes the challenge -- but this process is far more streamlined than trying to make everything fit together right from the start.
Second, there is lack of relationship and inverse models bridging the NDE-derived and conventional material properties compared to other disciplines of science, such as geophysics.
In the absence of sufficient mechanistic detail, the unknown or ill-defined part of a metabolic network can be substituted by an empirical (statistical) sub-model bridging the well-defined stoichiometry with a given cellular function, such as the synthesis of a complex recombinant product).
There is a need for models bridging the gap between these extremes; simulation techniques specifying finite, but possibly many, loci with specified effects (Bürger and Lynch 1995; Boulding and Hay 2001) could be useful here.
The rest of the paper concentrates on the model bridging Jackson and Wolinsky's (1996) connections model and Bala and Goyal's (2000a) one-way flow model.
The model bridges the gap between micro- and macro-level, and this is the novelty in the approach.
Parametric studies show that the model bridges the yield-slip (plasticity) theory and fracture mechanics, depending on platelet thickness, platelet aspect-ratio and matrix constitutive law.
In the model bridge, the number of beams in all spans was the same, resulting in identical dead loads.
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