In a recent study we showed that the development in fiber lengths during hydrolysis may indeed be successfully modelled based purely on the simple mechanical principles of 3-point bending (Thygesen et al. 2014).
Differently from previous models based purely on exogenous inputs (i.e. the platform motions), the NARX model relates the present value of the desired time series not only to the present and past values of the exogenous series, but also to the past values of the desired series itself.
The results indicate that simple models based purely on geometric factors are unlikely to be generally successful in predicting regioselectivity.
Furthermore, using computational modelling, they demonstrate that temporal coherence can at least qualitatively account for the results of behavioural experiments which models based purely on the activation of separate populations struggle to explain.
To address this issue, we have developed Bio-Logic Builder (manuscript submitted), a component of The Cell Collective, which allows laboratory scientists to build computational models based purely on the logic of the species' regulatory mechanisms as discovered in the laboratory.
The value of 0 leads to model selection based purely on the domain-dependent criteria, while the value of 1 leads to model selection based purely on the error E(m).
The layerwise shell model is based purely on a mid-surface NURBS description of the shell body thus supporting the direct application of a surface-defined CAD data representation of shells.
However, this naive linear model is based purely on genetic distance, and is contradicted by the large number of somatic mutations that are shared between the AA and H subpopulations, but absent from AB (for example, 2789 AA-H SNVs, Figure 2a).
