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3) Some aspects of the model are unclear.
D) The criteria for inclusion/exclusion of NF-kB pathway characteristics in the model are unclear.
On the other hand, the molecular mechanisms leading to the constitutive activation of mTORC1 pathway in the PGC-1β KO model are unclear.
Population age structure has been suggested to negatively affect the dynamics of CI and impeding infection spread [ 28], although the assumptions of this model are unclear.
Based on the loadings, high levels of PC and Glycine were observed in some tumors, but their influence in the classification model are unclear.
Ensemble measurements and electrophysiological sieving experiments show that the open-diameter of the channel pore is >25 Å, but the exact size and whether the conformational change follows a helix-tilt or barrel-stave model are unclear.
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However, because cytokines such as IL1 and IL18 also utilize MyD88 to activate downstream target genes [28] the involvement of the intestinal microbiota in this model is unclear.
How HIV infection impacts on this model is unclear.
1) The construction of the "passive model" is unclear.
Thank you. 1) The construction of the "passive model" is unclear.
The degree to which the pCODR and CDR will remain separate within CADTH's governance model is unclear.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com