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To assess the capacity of FastDC to induce antigen-specific T cell responses, FastDC were loaded with tetanus toxoid protein (TT) as a model antigen (Protocol 3).
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With carcinoembryonic antigen (CEA) as a model antigen, the presence of gold nanoparticles provided a congenial microenvironment for adsorbing biomolecules and decreased the electron transfer impedance.
Ovalbumin was used as a model antigen.
We have investigated the fate of amyloid as a model antigen in a cellular model of vaccination.
Expressed β-galactosidase was used as a model antigen.
This live virus vaccine maintains its ability to drive antigen-specific CD8+ T-cell responses to a model antigen as well as to the weakly immunogenic tumor antigen Her2/neu.
In order to evaluate the performance of the hybrid NPs as an antigen delivery system, a model antigen, keyhole limpet hemocyanin (KLH), was enclosed inside the PLGA core.
Three MHC class I peptides were used: one from model antigen OVA (SIINFEKL) and two from melanoma antigens, gp100 (KVPRNQDWL) and Trp-2 (SVYDFFVWL)[23, 23].
We have chosen HER-2 as a model antigen.
The participants were asked to quantify antigen-specific CD8+ T-cell responses against model antigens using their locally established IFN-gamma ELISPOT protocols.
OVA protein was selected as models antigens.
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