Sub-analysis for each outcome measure was performed for model-related factors (species, gender, model and timing of therapy) and cell-related factors (cell type, condition and origin, administration route and regime of therapy).
We performed subgroup analyses and meta-regression to investigate predefined factors that we hypothesised would modify the efficacy of cell-based treatment in CKD – cell-related factors (cell type, regime, condition, origin and delivery route) and model-related factors (species, gender, model and timing of intervention).
In the design of these studies to determine if BPA would predispose for mammary cancer, our first considerations were model, route and timing of exposure, and dose.
Today, Microsoft is announcing the business model and launch timing for Azure, the company's much hyped cloud operating system.
The exact role of γδ T cells in the synovial microenvironment of rheumatoid arthritis patients is currently debated, with murine models suggesting potentially pathogenic or protective roles for infiltrating γδ T cells, depending on the model system used and timing of antibody-mediated γδ T cell depletion [10,14,15,33].
We integrate these management states with field observations to model the rates and timing of phenology-based management states to identify when targeted grazing or mowing treatments are most appropriate using Dirichlet regression and multistate modeling.
Further, significant temporal changes in cytokine expression were observed in a rat CLP model of sepsis and timing of cytokine sampling must be considered [ 27].
Another possible limitation is that renal denervation could determine different results according to the animal model used, age and timing of the evaluation performed [ 6, 29, 31, 41, 42].
Under the independent model, the number and timing of gains and losses for each trait (e.g., habitat and the morphological trait) occur independently, whereas the dependent model provides additional parameters that affect the probability of a character's transitioning on a branch depending on the state of the other character.
Circuit simulation is used to characterize the cell library, memory models, and the timing critical portion of the circuit.
The presented Extreme-scale Simulator (xSim) permits running an HPC application in a controlled environment with millions of concurrent execution threads while observing its performance in a simulated extreme-scale HPC system using architectural models and virtual timing.
