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In this study, three-dimensional fragment based drug design (FBDD) combined with structure-based pharmacophore (SBP) model and structural consensus docking were employed to identify novel fXa inhibitors.
The 3D fault model and structural model are both established according to the unique structure map provided by CPEDC, reflecting the spatial geological characteristics of the study area and providing some guidance and help for oilfield development strategy to a certain extent.
The homology model and structural alignment of the homology model showed that the overall structure of DctP_00983 and DctP_01394 was very similar to the determined structures of other DctP-type SBPs.
It is very hard to rid ourselves of an incumbent model and structural bias.
The measurement model and structural model are estimated through partial least squares.
The use of filtration model and structural parameters can effectively predict the behavior of gas hydrates at negative temperatures.
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To confirm our molecular modelling and structural analyses, the crystal structure of nitrilase should be determined.
This paper deals with a multi-modelling approach for supervision using functional analysis, bond graph modelling and structural analysis.
We propose and describe a comprehensive theoretical framework that integrates choice models and structural equation models.
Factor Models and Structural Vector Autoregressions in Macroeconomics (with James Stock), in Handbook of Macroeconomics, Vol2A, John B. Taylor and Harald Uhlig (eds), 2016, Chapter 8, pp 415-526.
Possible functional consequences of the mutations were analyzed using protein modeling and structural mobility analyses.
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