Here we present results and numerical methods appropriate for studying our model, and closely related ones, in a unified and accessible form, hence allowing their direct application to epidemiological problems.
Bone metastases are a prominent feature of this model and closely resemble the osteolytic metastases frequently seen in breast cancer patients.
The MMTV-PyMT model was chosen because tumor progression has been extensively analyzed in this model and closely mirrors the progression of human disease [ 14].
Pharmacological inhibition with TGF-β receptor kinase inhibitors or tumour specific Smad4 knockdown disturbed invasion and metastasis in the zebrafish xenograft model and closely mimicked the results we obtained with these cells in a mouse metastasis model.
To assess the similarity of the garlic transcriptome to those of other model and closely related species, analysis of sequence similarity was performed using the BLAST Basic Local Alignment Search Tooll) algorithm with an E-value cut-off of 10−5 [ 59].
This model and closely related views of perirhinal cortex function (e.g., Eacott et al., 2001) predict that the perirhinal cortex is important for solving those visual problems where the repeat occurrence of the same or very similar visual elements makes the solution ambiguous.
