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Upon exposure to neutralized radicals containing fluorine atoms in a plasma, as model analytes, the conductance of the SWCNT matt showed fast modulation.
Using carcino embryonic antigen (CEA), prostate specific antigen (PSA) and α-fetoprotein (α-AFP) as model analytes, the proposed immunoassay exhibited excellent precision and sensitivity.
Using carcinoembryonic antigen and α-fetoprotein as model analytes, the simultaneous multiplex immunoassay showed linear ranges of over 4 orders of magnitude with the detection limits down to 0.5 and 0.8 pg·mL−1, respectively.
Using α-fetoprotein, human chorionic gonadotrophin-β, carcinoma antigen 125, and carcinoembryonic antigen as model analytes, the proposed immunoassay method showed high sensitivities and wide linear ranges in a simple, cheap and high throughput way.
Using cancer antigen 125 (Cand5) and carcinoma antigen 199 (Cas99) as model analytes, the simultaneous multiplex immunoassay showed linear ranges of over 4 orders of magnitude with the detection limits down to 0.02 and 0.04 mU mL−1, respectively.
Using α-fetoprotein (AFP) and carcinoembryonic antigen (CEA) as model analytes, the mixture including AFP, horseradish peroxidase (HRP -labeled anti-AFP antibody, CEA and HRP -labeledanti-AFP antibody was introduCEA into the SWIC for candying out tHRP-labeledincubation.
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Using carcinoembryonic antigen (CEA) as model analyte, the designed tracer showed linear range from 0.02 to 5.0 ng mL−1 with the detection limit down to 6.7 pg mL−1.
Using α-fetoprotein (AFP) as model analyte, the proposed method exhibits wide linear range of 0.001 0.1 ng mL−1 with a low detection limit down to 0.52 pg mL−1.
After the introduction of model analyte, the ferrocene (Fc -labeled antibody is immobilized on the sensing interFc -labeledibody–antibodyspecisimmobilized, resulting in a redon currentheignal.
Using insulin as a model analyte, the change of ECL intensity was logarithmically related to the concentration of the insulin in the range from 0.1 pg·mL−1 to 20.0 ng·mL−1 with a detection limit of 33 fg·mL−1.
Using miRNA-21 as model analyte, the designed nanosensor could detect miRNA down to 37 fM with a wide linear detection range of 1×10 13 M to 1.0×10-8 M, and exhibited good selectivity, acceptable reproducibility and low matrix effect.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com