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This model allows in vivo patch clamp recordings while the animal generates fictive movements.
For that reason, the model allows, in real-time, for the re-allocating of patients of a less urgent code and nature, to another day or week.
Our model allows in silico simulation of different nutritional requirements and constraints as they may be present in different host cell types or tissues that are difficult to directly address experimentally.
As AUC values computed from the data set used for model fitting tend to indicate better accuracy than the actual model allows in practice, AUC values estimated by the leave-one-out validation method and by 10-fold cross-validation method are also presented [ 35].
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Development of a predictive model allows in-silico screening of compounds in virtual libraries, i.e. before any compounds are actually made.
Both PCA models allowed in-depth evaluation of similarities and differences in the excipient properties.
Animal models allow in-depth studies of phenotypic variation associated with genes, which are impossible in human subjects (for example, genetic manipulations such as gene knockouts).
This model allowed in depth analyses of the migration of apatite forming Sr and F, from a glass-ionomer, Fuji IXGP (GC Corporation, Tokyo, Japan), into partly demineralized dentine.
Depending on the infectious agent's epidemiology, the model allowed in the worst case scenario only for an increase of HP (BSSF ≥1) between two consecutive surveys, whereas the alternative scenario allowed also for a decrease of HP between two surveys (BSSF values < 1 to ≥1).
Such modelling allows in virtuo experiments to complement the in vitro and in vivo methods that are already well-established in biology.
This realistic fluidic model allows for in vitro reconstitution of the microvascular environment using human cells and thus allows for screening of therapeutics on human cells.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com