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This model allows different sites to have different selection pressure, while there is no difference in different branches of the phylogenetic tree.
Note that the UniChem data model allows different sources to use identical src_compound_ids.
The proposed model allows different traffic loads to each network connection (heterogeneous traffic).
Moreover, the model allows different combinations of the time-driven or event-driven mode of the devices, including the samplers, the controllers and the holders.
CAD model allows different sub-systems to be modeled separately that not only prevents feature creation failures but also allows ease in modification of the model.
The simplest model, M0, assumes one ω for all branches, while the "free-ratio" or Mfree model allows different ω for all branches [34].
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An equation-oriented environment was selected to develop and implement the model, allowing different application instances, such as simulation, sensitivity analysis and optimization, to be easily performed.
To reveal selective changes after gene duplication, we employed a model allowing different ω values before and immediately after duplication.
We used a two-ratio model allowing different ω in foreground and background branches with PAML codeml.
The likelihood of a single ω (null model) was tested against the likelihood of a model allowing different ω in each branch (full model) using an LRT.
We then used HYPHY V.0.99 [ 56] to compare the likelihood of a model allowing different ω for HV regions and the rest of the protein with that of a model constraining them to be equal (the "fixed-sites" approach described in [ 57], LRT with one degree of freedom).
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