Sentence examples for model administration from inspiring English sources
In a murine model, administration of CD47-blocking antibodies or targeted inactivation of the Cd47 gene markedly inhibited SCLC tumor growth.
Regueira and colleagues [27] found that in an endotoxemic pig model, administration of NE was associated with an improvement of hepatic mitochondrial respiration and concluded that this effect was probably mediated by a direct effect of NE on liver cells.
They showed that in a human breast cancer xenograft mouse model, administration of antibodies against human-specific CD9 and CD63, which are enriched on the surface of EVs, significantly decreased metastasis, although no obvious effects on primary site growth were observed.
In this model, administration of DSS in the drinking water results in weight loss, intestinal epithelial cell damage and immune-mediated colonic inflammation.
In the rat proliferative glomerulonephritis model, administration of PP2 completely abolished the phosphorylation of c-Src and Smad1 and resulted in the amelioration of glomerulosclerosis.
Similar differences were also observed in an arthritis model: in a CIA model administration of IL27 systemically improves the clinical score, while in a proteoglycan-induced arthritis model the lack of WSX1 also improves the clinical scores [39], [40].
In experimental models, administration of lipoproteins protects against endotoxic shock [5] [7].
In murine arthritis models, administration of sgp130 reduced inflammation [ 28].
In all models, administration of osteoprotegerin results in an almost complete protection of the articular bone and disappearance of osteoclasts from the inflamed synovium [ 16, 26- 29].
In animal models, administration of GLP-1 and associated therapies reduced systemic hypertension and albuminuria, and ameliorated renal damage, as verified by histology.
In both rabbit models, administration of 130 mg/kg body weight rSP-C surfactant resulted in a far-reaching restoration of gas exchange and compliance.
