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We evaluated 54 original protocols, sent to us by the authors, and found that 74% (40/54) included an analysis section with a model adjustment plan.
We compared the model adjustment plan provided in the main trial publication with the corresponding information extracted from the registry, protocol, or design paper, to see if these did or did not agree.
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We assessed differences in the statistical plan for model adjustment between the trial protocol and the trial publication for those trials with available protocols.
They also compared the analysis plan for model adjustment in the published trial versus the trial protocol with information on the protocol collected from registries, design papers, and communication with all corresponding authors.
Information on analysis plan regarding model adjustment was available in 6% (9/162) of trial registry entries, 78% (21/27) of design papers, and 74% (40/54) of protocols obtained from authors.
Even then, analysis plans regarding model adjustment disagreed between the available information in the protocol and the published trial in about half of the cases.
Catalonia is on its fifth adjustment plan.
While that debate took place, Ms Rousseff failed to carry out her fiscal adjustment plan.
I needed to create an adjustment plan that would help me emerge successfully whenever my term would end.
Structural adjustment plans for the west, it seems, comprise of nationalisation, subsidisation and re-regulation.
Structural adjustment plans for the poor have involved privatisation, liberalisation and deregulation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com