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That the gene signature outperformed the prognostic model achieved by the PR status alone may be related to several factors.
To explore the importance of monocytes/macrophages, we used a macrophage-deficient model achieved by diphtheria toxin (DT) treatment of mice selectively expressing the diphtheria toxin receptor in CD11b + cells.
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Finally, the modeling achieved by GMDH will be used for Pareto based multi-objective optimization of geometrical parameters in new cyclones using NSGA II algorithm.
Finally, the modeling achieved by GMDH will be used for Pareto based multi-objective optimization of nanofluid parameters in horizontal flat tubes using NSGA II algorithm.
Experimentally, proof of principle studies demonstrated that inhibition of CXCL12-evoked CXCR4 signaling by respective blocking agents inhibited metastasis in experimental models, achieved by intravenous tumor cell injection [ 2426]6].
The predictive model achieved high accuracy evaluated by 10-fold cross-validations.
Verification of the model was achieved by comparing simulation results with experimental data.
An RFFR model is achieved by eliminating redundancy in the FFR model through clustering its set of conformations, thus generating subgroups, which should contain the most promising conformations [ 6].
The success of the proposed model is achieved by combining the 4 TFs and training the combined model while considering experimental binding information of the TFs to a sequence.
A final model was achieved by entering the variables retained in the backward selection model.
Further validation of the model was achieved by introducing much coarser particles in the feed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com