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We reported that in the pancreatic islet cell carcinoma RIP-Tag2 model, absence of CatS significantly reduced tumor growth [13].

Similar to us they found that in their model, absence of p55 TNFR resulted in reduced expression of MCP-1, VCAM-1 and ICAM-1.

In an experimental model, absence of protein tau alleviated the cognitive defects inflicted by amyloid [18], while expressing human wild-type tau causes no or minimal tauopathy [14] [17].

In saposin C-/ mouse model, absence of saposin C reduced GCase protein by ∼50% of WT levels and led to activity reductions, but GC and GS levels are not increased in the brain and visceral tissues [26].

In the final multivariate model, absence of coniferous forest and farm density were the major risk factors for F. hepatica exposure.

Interestingly, in the "bottleneck model", absence of sexual recombination of oDNAs is, to some extent, the driving force rather than the consequence of uniparental inheritance.

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In animal models, absence of TAM kinases is associated with lupus-like disease.

Other validity assumptions of the models (absence of interaction and collinearity, goodness-of-fit) were thoroughly verified.

In murine models, absence of Dicer leads to considerable disruption of cell function in T-lymphocytes, natural killer cells and Langerhans cells [ 37- 40].

Main reasons assessed are lack of mentorship and role models, absence of faculty development programs, financial issues and difficulties balancing work and family [ 6, 7].

Using multilevel models, absence of a previous ECT course(s) predicted a steeper rise in ST during the course (P = 0.03 for the interaction term time*previous ECT).

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