Exact(2)
We will then describe the C++ software, MaBoSS, developed to implement BKMC algorithm and finally illustrate its use with three examples, a toy model, a published model of p53-MDM2 interandion and a published model of the mammalian cell cycle.
Applications of the Boolean Kinetic Monte-Carlo are demonstrated for three qualitative models: a toy model, a published model of p53/Mdm2 interaction and a published model of the mammalian cell cycle.
Similar(58)
The new biomarker was added to the following: null model, model including a published risk score, model including a composite risk score estimated from the sample of interest, and multivariable model with individual predictors.
The GPS was derived by combining gene expression data obtained from the analysis of a cancer cell line model and a published colon crypt profile.
The deterministic two-patch population models followed a published framework [ 49] and were carried out in R v 2.6.2.
This model was compared to a published model derived solely from birth weights.
The model is based on a published Cav1.2 model [34].
We applied this algorithm to three different models: a toy model that illustrates a simple cyclic behavior, a published model of p53 response to DNA damage, and a published model of mammalian cell cycle dynamics.
For most soils, the new model results in a better agreement with observations than a published model.
This model is also benchmarked with a published numerical dynamo model solution.
Model 2 is a model published by Gennemark et al. [ 33] (equations for the model can be found in Additional file 2).
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