Sentence examples for model a mutation from inspiring English sources

To fully model a mutation, Pro-Maya also uses a content based-model and a MU-specific ΔΔG baseline-based model.

To generate synthetic data using a computer simulated evolutionary process, the researcher typically specifies four model components: a tree topology, a character substitution model, a mutation location model, and a probability distribution for the ancestral root sequence.

In order to precisely recapitulate an autosomal dominant hypertrophic cardiomyopathy mutation, we chose to model a mutation in the splice donor site of exon 15 in human TNNT2 (Thierfelder et al., 1994).

In one-phase models, a mutation leads to expansion or contraction of the microsatellite by 1 repeat unit only.

The FEL model revealed a total of 23 sites under selection using this model, including a mutation in the highly conserved small peptide ASARM (from aspartate to glicine).

Here, we generated a knock-in mouse model expressing a mutation that abolishes the ankyrin-G/GABARAP interaction (Ank3 W1989R) to understand how ankyrin-G and GABARAP regulate GABAergic circuitry in vivo.

An altered sensitivity of myofilaments to calcium ion concentration has been observed in an animal model with a mutation of this gene [31].

We used a Jukes-Cantor mutation model with a mutation rate of 10-5 per site and per generation.

All probands with a score of 80 or more according to the Manchester model carried a mutation.

Moreover, young mouse model harboring a mutation favoring generation of Aβ 1-42 over Aβ 1-40 had a low Aβ 40/42 ratio, was shifted to plaque deposition [ 45].

In summary, TWSG1-deficient mice represent a genetic mouse model of a mutation with low penetrance that sensitizes embryos to environmental influences.