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For tapping mode we used rectangular silicon cantilevers (nanosensors, 125 μm long, 30 μm wide and 4 μm thick) with a tip radius of about 10 nm, a normal spring constant of 40 N/m and resonance frequency of 339 kHz.
With slow capacitance compensation inactive in voltage-clamp mode, we used responses to a 10 mV hyperpolarisation step to estimate the neuron's membrane resistance (Rm; from the steady holding current at the new voltage) and membrane capacitance (Cm; from the area under the exponentially-decaying current from peak to holding).
Within each mode, we used the relative score formula as described in Section 'Relative scoring'.
Specifically, for the Gene2miR mode, we used >30 large-scale differentially expressed gene profiles that originated from miRNA overexpression experiments.
To investigate the resolution in z-direction for the pulse-echo imaging mode we used a crossed hair phantom as an object.
To evaluate the BYL system in dialysis mode, we used RTS Wheat Germ continuous exchange cell-free (CECF) devices (5Prime) and compared the BYL system to the two commercial WGEs from Promega and 5Prime.
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The other mode we use is a great entrepreneur with a track record will come to us and say, "Hey, I don't exactly have an idea, but I have an area I want to explore with you".
Alternatively, in direct-decision mode, we use decided symbols for the DFE feedback.
In the identification mode, we use the cumulative match curves (CMC), and rank-one recognition rate as a benchmark.
For the low current consumption of sleep mode, we use a digital multimeter that can capture extremely small current.
In the beamforming mode, we use the right singular vector corresponding to the maximum singular value of a given channel matrix.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com