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For example, all molecules containing a carboxyl group (C=O) will have a normal vibrational mode that involves the stretching of the carbon-oxygen double bond.
The most notable additions are the inclusion of female avatars for the first time, and a new "extinction" mode that involves fighting aliens instead of the usual zombies.
Now a large number of miRNAs are found to use an alternative binding mode that involves the bulging out of an unpaired mRNA nucleotide, leading to a functional mRNA-miRNA interaction.
The crystal structure of this complex suggests that WY14643 induces activation of PPARα in an unusual bipartite mechanism involving conventional direct helix 12 stabilization and an alternative mode that involves a second ligand in the pocket.
A smaller group of Type II NBs has a different proliferative mode that involves intermediate progenitors with transit amplifying cell divisions [15] [17].
It is generally accepted that the DNA glycosylase damage search process involves two major modes: an associative a mode that involves tracking along the DNA using a loosely associated enzyme state (often called "sliding") and a dissociative mode that involves intermittent dissociation and reassociation of the enzyme with the DNA chain ("hopping").
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Active commuting is using any mode, or mix of modes, that involves physical activity, explained Ellen Flint, a lecturer at the London School of Hygiene and Tropical Medicine and lead author of the study.
A simple optimisation methodology of the operating modes that involve these components is also presented.
Unlike most ring models, which only consider in-plane modes, the presented model also predicts the modes that involve torsion of the belt in circumferential direction.
This suggests a model whereby GR samples the IL6 promoter in several structurally distinct modes that involve both direct binding to the κBRE and tethered binding via protein protein interaction with DNA-bound transcription factors such as p65, and various coregulator complexes to disrupt NF-κB-mediated transcription.
Similarly, we observed a negative preference for drug administration modes that involve higher dosing frequency albeit the magnitude of the effect was small and close to zero.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com