Your English writing platform
Discover LudwigExact(4)
Historically, live-attenuated viruses have been our most effective mode of vaccination.
The increased breadth of the immune response against a live-attenuated virus may explain why this mode of vaccination has been so effective in preventing severe viral diseases such as smallpox and measles.
Until recently, Semple vaccination was the only mode of vaccination in countries such as India, where rabies is relatively common [ 7, 8].
Taking into account that peptides 8.1 and 8.3 were immunogenic in more than one mode of vaccination, we decided to further investigate the potential of peptides 8.1 and 8.3 to serve as TAA epitopes.
Similar(56)
The immungenicity of peptide epitopes may vary between different modes of vaccination (Firat et al, 1999).
The MAGE-A8 peptide immunogenicity was examined in three modes of vaccination.
All these modes of vaccination were proven to give efficient immunisation in mice (Porgador et al, 1997; Carmon et al, 2002; Firat et al, 2002).
Peptides 8.1 and 8.3 were found to be the most immunogenic in more than one of three modes of vaccinations, that is, both peptides can elicit an efficient immune response towards the same peptide-pulsed target cells.
A cutaneous administration by scarification is the most common mode of human vaccination, although subcutaneous (s.c).
The immunity induced by this mode of DNA vaccination does not completely prevent infection but passed the stringent test of protecting against lethal H5N1 challenge.
This might have two reasons: a), the modes of tolerogenic vaccination might not be very efficient, and b), the abundance of inflammatory effector/memory cells in adult humans might prevent induction and functioning of regulatory cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com