Sentence examples for mode of target from inspiring English sources
Molecular docking studies have inferred the possible binding mode of target compounds against integrase.
Molecular docking analysis was also performed to predict the possible binding mode of target compounds inside the hA3AR and hA2AAR.
The tumbling of truncated oval-nosed projectiles is very prominent, which results in the great uncertainty of deformation and failure mode of target plates.
The FHA domain is linked to the kinase/phosphatase catalytic domain by a flexible tether, and it exhibits a mode of target selection based on electrostatic complementarity between the binding surface and the phosphothreonine peptide.
Middle: FW H/V of target two-layered medium and SW H/Vs of three cap-layered media of which the depths of upper interface of cap layer are 2.5 times (gold), 5.0 times (red), and 10 times (blue) the wavelength (λ 0, corresponding to fundamental mode of target two-layered medium), and the S-wave velocities of cap layer (V sCap) = 2V s2V
The depth of upper interface of the cap layer is about (5 10)λ 0 A (product of thickness-weighted average S-wave velocity from surface to half-space of target layered medium and "apparent" predominant period of fundamental mode of target layered medium), and the velocity of the cap layer is about twice as large as the one in the half-space of given layered medium.
The dual specificity resulting from Sendai F-virosomal delivery and tumour specific activation offers a novel mode of targeting HCC at two levels, first by targeted liver cell specific delivery and secondly by promoter/enhancer driven expression only in transformed hepatocarcinoma cells.
This novel mode of target-specific binding, which neither belongs to lock-and-key nor induced-fit binding, is characterized by dimerization and continuous exchange between multiple flexible binding alternatives.
However, these microparticles could to be exploited in the future as a mode of targeted drug delivery.
We attempted to make this clear in the initial submission by discussing the CBX dependent hierarchical mode of targeting which highlights the fact that other mechanisms exist to target PRC1.
Our alignments of the SBS domain and the juxtaposed salt bridge-forming D451 residue reveal that this mode of targeting may also be conserved in other metazoan Ulp1-like SUMO proteases (Additional file 1).
