Sentence examples for mode of splicing from inspiring English sources

In males, where no functional Tra protein is available, the dsx pre-mRNA follows the default, male mode of splicing, which produces male DsxM protein.

Certain SNPs correlate with heritable changes in alternative splicing but do not cause disease, thus indicating a link between genetic variation and mode of splicing [29], [31], [32].

Trans-splicing of the voltage-gated sodium channel in response to nerve growth factor stimulation, further suggests that this alternative mode of splicing can be a regulated process [ 61].

Third, and perhaps, somewhat more disturbingly, I find the logic in the Discussion regarding exon definition being the ancestral mode of splicing to be weak, at best, and rather hard to follow.

This is especially the case for hnRNP A1 and A2/B1, which have been shown to antagonise, in a concentration dependent manner, protein members of the SR group, notably ASF/SF2, and to influence the mode of splicing of mRNA target molecules [ 12].

Alternative splicing in domesticated genes may have originated by mutations in splicing sites (evolution of weaker splice sites), by sequence changes in the intronic and exonic splicing silencers or enhancers (generating lower or higher densities) or by accumulation of Alu SINEs that can change the mode of splicing of the flanking exons [ 47, 48].

In contrast, yeast and other organisms with short introns the usual mode of splice site recognition is by intron definition.

The U1-70k isoforms 1 and 2 could therefore promote different "modes" of splicing, altering quaternary structures by strengthening interactions with U1-C and SmB/B' respectively.

First, the RUST hypothesis depicts that alternative splicing occurs through distinct modes of splicing events [ 26, 34].

Although these are the most common modes of splicing [ 41], a complete view of the genome-wide effects of splicing factor expression on the splicing process should also consider the other events regulated by splicing factors (alternative 5' and 3' splice sites, patterns of mutual exclusion, trans-splicing, and exon scrambling).

It was found that the clock genes, including EARLY FLOWERING 3 (ELF3) and ZEITLUPE (ZTL) that have not been studied in terms of alternative splicing, undergo extensive alternative splicing through diverse modes of splicing events, such as intron retention, exon skipping, and selection of alternative 5′ splice site.