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This suggests that the gradual mode of sequence evolution discussed above might be a general feature of short DNAs selectively driven or dragged to genomic over- or underrepresentation, including protein/transcription factor-binding, palindromic, repeated and other oligonucleotides.
The edges and parts of edges for which the gene or pseudogene mode of sequence evolution should be used is specified by Ψ.
It is thus conceivable that a deviating mode of sequence evolution in B. plicatilis (as described for hsp82 [ 28]) triggered an attraction of the bdelloid and acanthocephalan branches.
Relative rate tests [ 98] performed with MEGA 3 [ 99] revealed that a clock-like mode of sequence evolution could not be rejected (all P > 0.09), except for the hueii sequence as compared to G. praetermissa (P < 0.05).
To further characterize the mode of sequence evolution, we analyzed the distribution of amino acid usage (u), defined as the number of different amino acids observed per site in the sequence alignment (Breen et al. 2012).
However, the amino acid phylogeny of paralogous SSB1/SSB2 sequences from post-WGD Saccharomycetaceae species show a complex branching pattern not consistent with a divergent mode of sequence evolution (supplementary fig. S2 A, Supplementary Material online).
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SSLs reveal new modes of sequence cognition and overcome the limitations of current approaches that yield amalgamated "consensus" motifs.
Except from ω, these parameters are shared between the two modes of sequence evolution.
To more thoroughly examine evolutionary patterns and modes of sequence evolution within each of these Hsp70 subfamilies, we analyzed them individually by generating separate sequence alignments for each.
There are further modes of sequence evolution such as slippage events, insertions and deletions, large scale relocation of promoter regions, and recombination.
These results illustrate different modes of sequence evolution in class I retroelements and class II DNA elements in the T. cacao studied here.
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