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MaSCs are characterized by an asymmetric mode of division, generating one MaSCs and one progenitor per division, thus maintaining the stem cell pool.
This primary mode of division is often interpreted as a logical exercise.
In addition, we define two control points for determining a cell's mode of division.
This apical-basal polarity is thought to be of critical importance for the mode of division of APs, which can be either symmetric, with both daughter cells exhibiting the same fate, or asymmetric, with the daughters exhibiting different fates.
We also contend that the model provides a sensitive meaningful read-out of self-renewing symmetric NSC division, as expansion of this population is dependent on this mode of division.
Interestingly, Wnt/PCP signaling has been previously reported to regulate oriented cell division during gastrulation, allowing axis elongation [61], [62], and to regulate asymmetric cell division [63], which is the predominant mode of division used by VM progenitors during DA neurogenesis.
Similar(42)
Even under a light microscope, differences can be seen in the modes of division among diverse groups of protists.
The challenge is in the dynamic nature of the process and multiple cell types involved, each having several potential modes of division or cell fate.
The most important material for our purposes is Boethius' treatment of the first and second substantial modes of division.
If the spacing of the cells in the head uses the same cellular operations as in the trunk these operations could be combined with different modes of division, suggesting a modular organisation [51], [52] of these operations.
The transition between the two modes of division is dependent on the Notch signalling pathway.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com