Sentence examples for mode of cell migration from inspiring English sources
Interestingly, while elevation of miR-200a levels led to the mesenchymal mode of cell migration, elevation of miR-200c levels led to the amoeboid mode of migration, highlighting new roles of this microRNA family in switching or plasticity of modes of tumor cell migration.
Along this vein, several previous studies implicated the random mode of cell migration in tumor progression.
This illustrates the important role of carcinoma cell TGF-β signaling in determining the mode of cell migration and invasion.
Conceivably, by regulating microtubule dynamics, NAV3 inhibits the random mode of cell migration and restrains dissemination of tumor cells.
In other words, the quantitative modeling we performed implied that loss of NAV3 would bias the random mode of cell migration.
The encoded protein binds with the tips of microtubules and enhances their growth, while augmenting the directional mode of cell migration.
Our panel of cell models, spanning a wide spectrum of phenotypic plasticity, supports the investigation of different modes of cell migration and tumor morphologies, and will be useful for predictive testing of anti-cancer and anti-metastatic compounds.
It has become clear that cancer cells have multiple modes of cell migration during tissue invasion: collective, individual elongated or "mesenchymal-type," and individual rounded or "amoeboid-type" [1], [3], [4].
Numerous publications have demonstrated that differential modes of cell migration can correlate with altered metastatic ability.
Investigation of the mechanisms and modes of cell migration is therefore important for fundamental scientific insight and for translational research, as molecules involved in deregulated cell migration are attractive targets for therapeutic intervention.
Yet, recent comparative studies have started to show that important differences also exist among mammals, concerning the topographical location of neurogenesis, the internal arrangement of adult neurogenic sites, and the mode/direction of cell migration (reviewed in [33]) [33].
