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Structural data on the dual binding mode have typically been collected using a mutagenesis approach, where one of the binding modes was destabilized by mutating key recognition elements (Carvalho et al., 2007; Pinheiro et al., 2008).
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Constraint-based methods, such as elementary flux mode analysis, have typically a high computational cost stemming from a large number of steady-state pathways in a typical metabolic network.
Studies have typically considered only mode-I (opening) fracture, but many observations demonstrate the significance of mode-II (sliding) fracture for better design of pavement structures and damage characterization of asphaltic materials.
While these techniques have provided some useful information regarding the effects of amorphogenesis-inducing proteins on (ligno) cellulosic substrates, they have typically provided little insight into the mode of action of these proteins.
However, the risk assessment and retrofit methodologies for these bridges have typically only been developed around a single failure mode.
Producers have typically not been recognized.
Depeche Mode have to be careful.
Previously, antigovernment rallies had typically been quashed.
Each mode has trade-offs.
But each mode has something to offer!
Typically, the power consumption of a hard disk can be broken down into three major parts: startup, idle, and accessing modes, where each such mode has different power consumption behaviour.
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CEO of Professional Science Editing for Scientists @ prosciediting.com