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In this mode, data acquisition is also prospectively triggered with the ECG of the patient.
Scatter correction was not performed because of the use of 2D mode data acquisition.
A 60-minute microPET list mode data acquisition was started 2 - 5 seconds prior to an i.v. FDG bolus (18.1 ± 5.5 MBq in 30 μl).
Therefore, the phantom data interval to be extracted for list mode data acquisition is 355 s for the Hoffman phantom (20 MBq at start) and 180 s for the cylindrical phantom (40 MBq at start) under standard scanning conditions.
After a transmission scan for 15 min using a 68Ge-68Ga rodation rod source, 18F-BCPP-BF at ca. 15 MBq was intravenously injected into each rat via the tail vein, and this was followed by an emission scan with list mode data acquisition (every 1 ms) for 90 min.
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PET list mode data acquisitions were performed on two widely used clinical PET/CT systems: Siemens Biograph 64 Truepoint TrueV (Siemens Healthcare, Erlangen, Germany) and GE Discovery 690 (GE Healthcare, Milwaukee, WI, USA).
The use of a list-mode data acquisition technique enabled simultaneous determination of 22Na and 7Be activity concentrations using a single measurement by coincidence and anticoincidence mode respectively.
List-mode data acquisition and flexible hardware design ensures that the most sensitive coincidence schemes involving β, atomic electron, γ and X-ray emissions can be used for radionuclide quantification.
For the C-erlotinib PET/CT study, 500 MBq±10% C-erlotinib was administered intravenously and immediately followed by a dynamic PET recording of the thorax for 90 min using list-mode data acquisition.
The system operates in 3D mode and data acquisition is done in list mode.
The mass spectrometer was operated in electrospray negative mode, and data acquisition was in multiple reaction monitoring mode (MRM).
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