In practice, pilots have to be very much in the loop, ready to intervene ("pick up the slack," as they say) when flight plans suddenly change, or one or other of the plane's automated systems starts functioning in a reduced operating mode, contributing to the so-called "minimum equipment list".
This Ub binding mode contributes to Ub specificity and is distinct from that observed in other deubiquitinating enzymes.
The destructive interference of the quadrupole mode (dark mode) with the dipole mode (bright mode) contributes to the origin of the Fano resonance.
Failure surface characteristics, including mixed tensile and shear segments, indicate hybrid failure in chalk and limestone, whereas shear failure predominates in mudrock and ash beds – these changes in failure mode contribute to variation in fault dip.
It is shown that the modal responses, when defined at a non-exceedence probability of 0.84, would give relatively accurate values of design response only if the individual modes are perfectly correlated or a single mode contributes to the particular response quantity of interest.
By selectively utilizing "effective" information in local regions of the time frequency plane, where only one mode contributes to energy, the proposed technique can successfully identify mode shapes and recover modal responses from the non-stationary response where the traditional SI methods often encounter difficulties.
In addition, Ca2+ entry via NCXpm operating in reverse mode contributes to intracellular Ca2+ overload under pathological conditions such as myocardial ischaemia and reperfusion (Lee et al., 2005).
Given that NCXpm is an electrogenic transporter, NCXpm operating in the forward mode contributes to a faster decay of the hyperpolarization and intracellular Ca2+ rise.
Recent findings indicate that in endothelium from rat aorta exposed to ATP, NCXpm operates in the forward mode contributing to the restoration of internal Ca2+ (Berra-Romani et al., 2010), suggesting that the mode of NCXpm operation is agonist-specific.
