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CT provides the mainstay modality for surveillance on grounds of good overall diagnostic performance combined with high availability and low cost, rather than greatest sensitivity for detection of tumour recurrence.
The conventional serological diagnostic test, estimation of serum alpha-fetoprotein (AFP) lacks both sensitivity and specificity as a screening tool and improved tests are needed to complement ultrasound scanning, the major modality for surveillance of groups at high risk of HCC.
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Technology has evolved significantly, with new applications and means of communication being developed on an almost daily basis, including new modalities for surveillance.
Currently ultrasonography (US) is the recommended screening modality for periodic surveillance for HCC in at-risk patients.
However, as for MRI, the high cost and lower availability of PET precludes the use of this modality for routine surveillance.
Venous duplex ultrasound (VDU) is the modality of choice for surveillance of venous thromboembolism (VTE), but there is controversy about its appropriate implementation as a screening method.
However, their use in targeting high-risk groups on a population basis for the impact on modalities of screening, intervals for surveillance, or preventive therapies or strategies remains important.
The fact that the pain subscale and activity level are such strong predictors for disease-free survival suggests that in the future these measurements might even be used as surveillance modality for recurrent disease; a low score on these subscales could be an indication for further diagnostic imaging.
Patients with LOPS should be educated on ways to substitute other sensory modalities (hand palpation, visual inspection) for surveillance of early foot problems.
Patients with loss of protective sensation should be educated on ways to substitute other sensory modalities (hand palpation, visual inspection) for surveillance of early foot problems.
Self-reported measures for surveillance of periodontitis.
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