This work has highlighted the potential of combining multi-modality characteristics to differentiate the core of the tumor from peritumoral tissues and normal tissues, and thus to provide richer information on lesion status than individual imaging modalities [ 20, 21].
However, distinct discrepancies between our results and previous studies were also observed due to differences in neuroimaging modalities, characteristics of subjects, and metrics for defining global hubs (such as the node degree, the nodal efficiency, the characteristic path length, and the node betweenness).
Equally important, analyses of secondary outcomes and moderator and mediators of treatment response have, and will continue to, provided clinically-relevant information for matching patient characteristics to treatment modality to better personalize care and maximize patient outcomes.
We studied each modality separately and revealed their own characteristics to set the stage for the integrative study.
Data were collected on study design, treatment modalities, characteristics of the sample, methods of measurements, success rate, decrease of open bite and divergency, treatment duration, side effects and costs, and stability.
The dual-modality characteristics of the designed particles could assure that only those DCs that have taken up the antigen, and hence are responsible for an immune response, are traceable via 19F-MRI.
Regarding MSC use in the treatment of treat lung diseases, these cells represent a promising modality due to their characteristic migration to injured tissue, intrinsic immunosuppressive properties and plasticity to differentiate into mature lung cells required for the lung repair [ 13].
The use of multimodal neuroimaging technologies has the advantages to overcome the limitations of any individual imaging modality and to aggregate clinical characteristics and features obtained from different imaging techniques for knowledge mining and for guiding medical diagnosis and decision making [2].
The attending physician was responsible for indicating the proper therapeutic modality according to patients' individual characteristics (comorbidities, clinical status, disease sites, and personal preferences).
Research is required into optimizing screening frequency and modality according to the breast tissue characteristics of women.
This study evaluated the prognostic value of different neuroimaging modalities, clinical characteristics, and their combination to classify MDD course trajectories.
