Sentence examples for modalities that target from inspiring English sources

Theoretically, identification and characterization of the CSCs may allow the development of treatment modalities that target the cancer stem cells rather than the rapidly dividing cells in the cancer.

Preservation of the breast cancer microenvironment is critical for evaluating therapeutic agents especially when designing modalities that target invasive disease.

It is becoming clear that combination or sequential treatment modalities that target multiple pathways can lead to better control of aberrant cell proliferation.

It is crucial to develop clinically relevant novel combination regimens involving synergistic modalities that target a wider repertoire of cells and lead to lowered individual doses.

Our results show a marked defect in DDR activation with DMC1 depletion and combination of a DMC1 inhibitor with treatment modalities that target various DNA repair pathways could effectively target GBM cells.

The challenges before us are, on one hand, to discover novel treatment modalities that target essential steps that are involved in the development of IBC, such as those directed against its angiogenic and angioinvasive potential.

Video-based coaching is an educational modality that targets intro-operative judgement, technique and teaching (Hu et al. 2012).

Combination therapy with MET tyrosine kinase inhibitors and standard chemotherapeutic agents and the anti-EGFR antibody cetuximab is another treatment modality that targets the HGF/MET pathway.

This will likely facilitate defined treatment modalities that selectively target this large subset of tumours.

The importance of identifying new therapeutic modalities that directly target the signaling pathways constitutively activated by mutant TNFR1 is thus apparent.

We strongly believe that identification of mediators of translation such as eIF4E may enable future design of therapeutic modalities that can jointly target several pro-malignancy factors at once.