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Survivors received all modalities of diagnostic imaging at significantly higher rates than controls.
We determined receipt of 5 modalities of diagnostic imaging and associated radiation dose received by survivors and controls from years 5 15 after diagnosis or matched referent date through administrative data.
The registry systematically records data on sociodemographic status, diagnostic circumstances, modalities of diagnostic assessment, tumour characteristics coded according to the International Classification of Diseases for Oncology WHO (1976), stage of the disease at diagnosis, treatment during the first 6 months after diagnosis, survival status and cause of death.
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CT is generally the first-choice modality of diagnostic imaging.
However, fMRI cannot be considered as a fully established modality of diagnostic neuroimaging due to the lack of guidelines of the responsible medical associations as well as the lack of medical certification of important hardware and software components [ 19].
> -wrap-foot> computedtomographyaPET, positrontron emission tomography, MRI magnetic resonance imaging, NR not reported, SD standard deviation, CDM conventional diagnostic modalities Estimates of diagnostic performance, such as sensitivity, specificity, positive and negative predictive value, accuracy, DOR and AUC for all individual studies are shown in Table 3.
With the increasing number of applications for peptide-based radiopharmaceuticals, new radiolabelling strategies are of high interest in particular for "theranostic" agents [1], which combine the modalities of therapy and diagnostic imaging [2].
Originally introduced by Funkhouser in 2002, the term "theranostics" describes any "material that combines the modalities of therapy and diagnostic imaging" into a single package.
One article evaluated the accuracy of a combination of diagnostic modalities to detect lesions without specifying individual accuracies per modality and was thus excluded [ 46].
For this reason, a number of diagnostic modalities have been proposed, including laparoscopy, clinical scoring systems, computer programs, ultrasonography, CT scans and MRI [7 9].
However, new cases of sarcoid are increasingly diagnosed in TB endemic areas in recent years due to increased awareness and better availability of diagnostic modalities.
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