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HER2 copy number gains were also assessed by aCGH in the Spanish cohort as an exploratory analysis, and while there was significant overlap with the other modalities of assessing HER2, there were many specimens which were discordant (Fig. 3).
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The greatest advantage of choline PET/CT is that it is a whole body, noninvasive imaging modality capable of assessing the disease recurrence in multiple anatomical sites with higher accuracy than conventional imaging and FDG PET [ 2].
A survey was performed to assess sertindole's modalities of prescription, assess and document any serious adverse events (SAEs), and assess the mortality rate within the NPU cohort.
CT is the primary imaging modality for assessing response of disease to treatment.
Whereas CT is the preferred modality for assessing morphology of the heart and the coronary arteries, CT might also play an important role in functional assessment as well.
The simultaneous use of three different modalities to assess different aspects of tissue microvascular function was an important strength of this investigation.
Biopsy is the gold-standard modality for assessing the degree of fibrosis and for evaluating necrosis or inflammation.
Coronary angioscopy is a useful imaging modality for assessing the characteristics of atherosclerotic plaques in vivo (6– 11).
Because SUVmax was positively correlated with the expression of pAkt (Ser-473), pAkt (Thr-308) and pS6, F-FDG PET might be a useful imaging modality for assessing the biological characteristics of RCC from a molecular point of view.
Nevertheless, their advantages, as discussed here, make them a very promising preclinical platform, and a potential means of assessing complex treatment modalities and of identifying anti-cancer drug combinations to evaluate in the clinic.
Further limitations included the fact that they were reported only in subsets of participants in some studies, lack of common definitions for cardiac outcomes, and lack of common monitoring either in terms of modality to assess cardiac outcome or in terms of timing and duration of monitoring.
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