These models, where the initiating antigen is well defined, are very valuable for testing different modalities of antigen-specific interventions.
The boosting of specific immune responses upon i.vag administration indicates that LSDFs are viable mucosal vaccine delivery modalities promoting antigen stability and facilitating intimate exposure of CN54gp140 to the mucosal-associated lymphoid tissue of the female genital tract.
Delayed antigen release from NPs may reduce loss of antigen during circulation and increase bioavailability of antigen to DCs, thereby enhancing immune response.
Moreover, varying modalities have been used to induce DC maturation in these comparative studies, e.g., TNFα, lipopolysaccharides or CD40 ligation [ 12, 13], as well as different sources of antigen, e.g, soluble protein and apoptotic cells [ 12– 12].
Therefore, the development of novel treatment modalities, including antigen-specific cancer immunotherapies with peptide vaccines, dendritic cell vaccines, and adoptive cell transfer therapies, is critical for advancing effective cancer treatments [ 3– 5].
The modalities of withdrawal need obvious attention.
'It's not about peace or war, but the modalities of making peace.
Psychologists and cognitive scientists are, like Molloy, still struggling to understand the role and modalities of inner speech.
Ethical modalities of architecture.
Modalities of circulation are exposed.
They support multiple modalities of locomotion and manipulation.
