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Furthermore, if we were able to control the mobilization of endogenous osteoprogenitor cells, large-scale surgery may no longer be necessary.
These findings suggest a promising possibility that mobilization of endogenous glial progenitors can provide a therapeutic opportunity to repair the white matter damaged by traumatic SCI.
Nonetheless, the integration of functional new neurons following injury can be achieved by the mobilization of endogenous stem cells [8], [9] or by transplanting new cells from different sources, as shown in experimental models of ischemia [10] [12].
The phylogenetic analyses suggest that the CfERV-Fc have evolved as exogenous retroviruses that successfully infected the ancestral canid population in bursts, possibly followed by mobilization of endogenous retroviruses.
To rule out the possibility that the observed Aβ inhibitory activity is due to or influenced by mobilization of endogenous TSP1, we used TSP1 null cells to evaluate Aβ inhibition of NO signaling.
Activation of group I mGluRs by DHPG affects synaptic transmission in various ways [6], including the mobilization of endogenous cannabinoids (endocannabinoids, eCBs [7], [8]) and induction of eCB – mediated forms of short and long term synaptic plasticity [9], [10] by activating the cannabinoid receptor, CB1R.
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These findings suggest that blocking receptor activation by endogenous LPA and S1P may be critical to the successful mobilization of either endogenous or exogenous neural progenitors for therapeutic recovery from neural injury or neurodegenerative disease.
Mobilization of this endogenous cell pool reduces stroke damage.
In rice, rampant mobilization of an endogenous MITE transposon, mPing, was detected in selfed progenies of the etoposide-treated plants in one of the studied cultivars, pointing to transgenerational genomic instability by the drug treatment.
The inhibition of inflammatory reactions via the paracrine effects of exogenous hMSCs might have helped to stabilize injured vascular regions through the mobilization of more endogenous bone-marrow-derived cells to the peripheral circulation.
Such knowledge is essential for the development of innovative therapeutic strategies based on the mobilization and targeted activation of endogenous neural stem cells for tissue repair.
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mobilization of would-be
mobilization of myeloid
mobilization of geochemical
mobilization of curarized
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mobilization of national
mobilization of internal
mobilization of domestic
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