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Therefore, the inhibitory effect of 2-APB on carbachol-induced ERK1/2 activation and Ca2+ mobilization is likely to be occurring through an action at SOCs, another known target of this inhibitor [ 31].
In this setting, social insecurity and costs linked to vaccination may jeopardise the use of OCVs especially for socially marginalized individuals and groups, and social mobilization is likely to be key for the success of any vaccination campaign.
Experiments using engineered L1 reporter systems have shown that L1 mobilization is likely to occur via TPRT in neuronal precursor cells and may be altered by neurological disease (Coufal et al., 2011; Coufal et al., 2009; Muotri et al., 2005; Muotri et al., 2010).
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Since PKC activation is usually accompanied by ER calcium mobilization, it is likely that this signal could trigger the retrotranslocation of GIIβ, thus becoming accessible to PKC.
Mobilization of RTEs is likely to be an important contributor to the progressive dysfunction of aging cells.
We suggest that somatic retrotransposition is a potentially important aging process that can affect many tissues, and that the mobilization of RTEs is likely to be a significant contributor to the progressive dysfunction of aging cells [ 48].
This mobilization is most likely due to chemical modification of the rhizosphere by root exudates.
Mobilization is not likely to contribute to hyperlipidemia, since we saw the same pattern of lipid profile in BC patients and in the age and sex-matched non-cancer portuguese population [ 67, 68].
Many groundwater samples plot near the boundary between goethite and aqueous ferrous iron, suggesting that reductive dissolution of HFOs and resulting mobilization of adsorbed As is likely.
The slower mobilization of cellular proliferation therefore is likely due to the lack of coordination of various pathways participating in the mobilization process.
Mobilization of lead from bone is likely to occur during periods of altered mineral metabolism; since calciotropic factors determine the uptake and storage of lead in this compartment, changes in calcium-related regulatory factors are likely to affect lead compartmentation.
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