Sentence examples for mobilization effects from inspiring English sources
When given in combination, G-CSF plus plerixafor are synergistic in mobilization effects.
Finally, no correlation was found between plerixafor dose escalation and mobilization effects on WBCs, blasts, CD34+ cells, or FISH+ cells (Supplementary Table 11).
This may represent continued effect of G-CSF plus plerixafor, mobilization effects of chemotherapy, or slow kinetics of busulfan-induced myelosuppression, which occurs in a time-dependent fashion, and possibly in an apoptosis-independent fashion.
Moreover, the concurrent inhibition of VLA-4 and CXCR-4 has a synergistic mobilization effect in primates [ 104 ].
Of note, the mobilization effect of CXCR4 antagonists was not limited to CXCR4high cases, suggesting that blockage of CXCR4 is not the unique reason for AML cell mobilization.
11– 16 Further, plerixafor synergistically augments the mobilization effect of G-CSF on CD34+cells. 5 Hematopoietic differentiation of transplanted CD34+cells was similar after plerixafor or G-CSF mobilization methods.
This mobilization effect in CEP levels may facilitate tumor cell repopulation during the common time intervals between the individual chemotherapy cycles [ 33].
Studies in mice, primates, and humans have shown that the administration of the anti-VLA-4 monoclonal antibody (natalizumab) or blockade of its ligands leads to a potent mobilization effect [ 23, 28, 58 ].
Several DM patients have been treated with high-dose hrG-CSF in cell therapy protocols (31), but a formal comparison of the mobilization effect between DM and non DM patients never has been performed.
To measure the mobilization effect of the community-based interventions, women who had participated in AWSOTM or who had attended community-based activities or sermons and who had unmet health needs were given a "referral card" to take to an MCH center when they sought services.
Sricharoenchai in an observational study conducted in Baltimore ICU over 30-month period including 5267 activities showed a low incidence of early mobilization adverse effects (0.6%) [2].
