Sentence examples for mobilization differentiation and from inspiring English sources

These studies have led to the hypothesis that SDF1 plays an important role in EPC mobilization, differentiation and homing.

Secondly, it is possible that the relationship of SDF1 with EPC mobilization, differentiation and homing in the acute phase is different from that in the normal situation.

SDF1 has a crucial role in stem cell mobilization, differentiation, and homing and also is a highly potent chemoattractant for monocytes and naive T cells [3], [4].

All these findings from animal studies strongly suggest that SDF1α has a crucial role in stem/progenitor cell mobilization, differentiation, and injured tissues-specific homing.

Thirdly, because SDF1α functions as a chemoattractant for stem/progenitor cells, the SDF1α gradient between bone marrow, peripheral blood and injured tissue/sites is crucial for stem/progenitor cell mobilization, differentiation and homing[26], [34] [36].

Moreover, previous study showed that EPC number is, at least in part, genetically regulated[29], and the presence of SDF1-3'allelele was a predictive factor of CD34+ cell mobilization[30], which prompt us to hypothesize that the SDF-1 gene single-nucleotide polymorphism (SNP) might involve in their gene transcription and progenitor cell mobilization, differentiation and homing.

This review highlights the recent advances in our understanding of the mechanisms of stem cell mobilization, provides newer evidence implicating bioactive lipids in BMSPC mobilization and differentiation, and discusses their potential as therapeutic agents in the treatment of IHD.

There is emerging evidence indicating that variation in the human SDF1 gene can have an influence on SDF1α levels[28], [28], which was demonstrated clearly to be involved in progenitor cell mobilization and differentiation in human and animal studies.

During the postoperative period, the in situ regeneration was boosted by administering bioactive molecules to promote peripheral mobilization and differentiation of stem/progenitor cells and ultimately the regenerative process.

The EPCs plays critical role in postnatal vasculogenesis through pivotal bioactivities of mobilization, homing, migration, differentiation, and proliferation in angiovasculogenic tissues [ 6].

In line with these considerations, recent advances in molecular EPC mechanisms highlight involvement of different growth factors and signaling pathways (i.e., VEGF, TGF- β, ROS, Wnt, Notch, and TLR-4 pathways) and microRNA in EPCs mobilization and differentiation into mature ECs [ 79, 80].