Sentence examples for mobility of loop from inspiring English sources

Changing the mobility of loop 1, either increasing or decreasing mobility, results in a lower activity.

Either destabilizing helix 3, changing the mobility of loop 1, or both results in a decrease in activity.

Collectively, our data show that sites other than V266 can induce similar effects by destabilizing helix 3, affecting the mobility of loop 1, or both.

The steric clash mutants decreased activity by either affecting the position of helix 3, affecting the mobility of loop 1, or both.

Likewise, the mobility of loop 1, possibly in combination with maintaining the H-bond between H121 and T62, appears to affect activity, particularly with regard to movement of M61 to a solvent-exposed position when H121 rotates toward C163.

As a result of these changes, the volume of the interface is decreased by ~800 Å, the S1′ pocket is narrower, and the mobility of loop 1 is increased.

It has been shown that the residue H407 and several other residues on this loop are required to reduce the mobility of the loop so electron density corresponding to it can be seen once the pre-decarboxylation intermediate is formed.

It has been shown in an analysis of chimeric loop-1 mutants of smooth muscle myosin that the mobility of this loop correlates to the rate of ADP release [ 31].

The mobility of the loop was reduced by introducing a new disulphide bridge in the mutant D241C/D249C.

Regardless, it is speculated that the mobility of this loop may possess a biological function in SsTroA [26].

In these enzymes there is a significant decrease in mobility of the loop upon inhibitor binding [ 48, 51] and it moves towards the bound inhibitor [ 16].