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Their mobility is regulated according to their primary tasks.
Cell adhesion strength, arrangement of cytoskeleton, and gene and protein expression levels of adhesion-related proteins were studied to corroborate the mechanisms, demonstrating that the cell mobility is regulated by the complex and synergetic intracellular signals resulted from the difference in surface properties.
Furthermore, although it appears that U1-70K moves by diffusion its mobility is regulated by phosphorylation and transcription.
Using a GFP-SR45 fusion protein, we showed that SR45 localizes to nuclear speckles and its mobility is regulated by ATP and transcription [19], [20].
The cell mobility is regulated by the formation of an intracellular actin cytoskeleton and FA formation.
In hermaphrodites, this decrease in mobility is regulated by insulin signaling [ 17] and in males by the NAD+-dependent metabolic regulator SIR-2.1 [ 18], suggesting a potential role for glucose in this process.
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With FRAP analyses, we show that inhibition of transcription and protein phosphorylation and dephosphorylation slowed its mobility, indicating that the mobility of U1-70K is regulated by transcription and the phosphorylation status of the cell.
According to the regulated nucleosome mobility model, chromatin is regulated by factors that control the equilibrium between nucleosomes with low and high mobility [27].
RAGE expression is regulated by multiple ligands, including high mobility group box-1 (HMGB-1), and is reflected by its released soluble form (sRAGE).
With the help of electronic mobility shift assays (EMSA), Beak et al. found that CFL2 is regulated by Rim101 but not by Hap3 [ 46].
The activity of CR4.2 is regulated by Meis1 transcription factor as demonstrated by electrophoretic mobility shift assay (EMSA) and site-directed mutagenesis assay.
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