Self-diffusion studies using fluorescence recovery after photobleaching (FRAP) and bulk release studies indicate that macromolecule mobility within, and release out of, these gels can be modulated by varying the hydrogel mesh size.
The mechanism of action of colchicine remains incompletely understood, but colchicine binds to tubulin and evidently modulates neutrophil adhesion, mobility, and cytokine release in a presumably rather specific manner in patients with defective pyrin variants [ 20, 21].
Vaginal rings releasing both zidovudine (AZT) and non-hormonal contraceptive molecules (such as ferrous sulphate and ascorbic acid) have been found to be effective in vitro in inhibiting sperm mobility and they released sufficient amounts of AZT to inhibit HIV proliferation (Han et al., 2007).
Immunogenic cell death is characterized by the pre-apoptotic exposure of calreticulin (CRT) on the cell surface, post-apoptotic exodus of the chromatin-binding protein high-mobility group B1 (HMGB1) and release of ATP.
Drying of the PS-ox sample at room temperature removes the physisorbed water that reduces proton mobility at the interface and release fraction of the holes trapped at donor-acceptor centers.
Iron (oxyhydr oxides may act as a sink and source of arsenic (As) in terrestrial and aquatic systems, therefore studying the mechanisms controlling Fe (oxyhydr oxide transformation under changing environmental conditions is essential for elucidating the fate of As, in terms of release, mobility and speciation.
It is associated with decreased nuclear expression of lamin B1 (Freund et al., 2012) and release of high-mobility group box 1 (HMGB1) proteins (Davalos et al., 2013).
Recently, the unique ability of doxorubicin, daunorubicin and mitoxantrone to make cancer cells immunogenic was shown to be through calreticulin re-localization to the cell surface [ 10] and the selective induction and release of High-mobility group box 1 (HMGB1) protein from dying cancer cells [ 11].
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