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However, our goal was to demonstrate the feasibility of creating an entirely integrated and portable mobile phone microscopy system.
As an example, mobile phone microscopy as demonstrated here could provide a rapid, point-of-care method for monitoring TB patients.
Combining the mobile phone microscopy system with automated sample preparation systems could address challenges associated with use by minimally-trained health workers and the time involved in imaging multiple fields of view [24].
By using existing communication infrastructure and expanding the capability of existing mobile phone technology, mobile phone microscopy systems could enable greater access to high-quality health care by allowing rapid, on- or off-site microscopic evaluation of patient samples.
This mobile phone microscopy system could prove to be particularly useful for point-of-care screening of newborns for sickle cell disorders, to identify and treat patients before the onset of symptoms in resource-poor nations, a process already mandatory in the United States and other developed countries [17], [18], [19].
While future field studies are planned to evaluate the reliability and ease of use of mobile phone microscopy, our present system serves as a proof of principle that clinical imaging of hematologic and infectious diseases is possible with conventional mobile phone camera technology combined with a custom microscopy attachment.
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Recently, mobile phone-based microscopy platforms are emerging to provide alternatives to conventional benchtop microscopes; translation of mobile phone devices into hand-held microscopy platforms relies on the creation of lightweight, compact, and mechanically robust imaging attachments that can be added onto the existing camera module of the mobile phone.
Our initial device development efforts have been aimed at using the digital imaging capabilities, mobile connectivity, and computational power of a camera-enabled mobile phone to capture high-resolution microscopy images and perform subsequent image transmission or analysis.
We expect such a telemedicine system for global healthcare via mobile phone – offering inexpensive brightfield and fluorescence microscopy integrated with automated image analysis – to provide an important tool for disease diagnosis and screening, particularly in the developing world and rural areas where laboratory facilities are scarce but mobile phone infrastructure is extensive.
We have developed a microscope attachment for a camera-enabled mobile phone such that it can be used as a platform for high-resolution clinical light microscopy.
My mobile phone.
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