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Selenium in samples 1 and 2 was also positively correlated to As, Cu, and Mn (data not shown).
From a diagnostic point of view, a positivity cut-off of >20 has similar significance for H5pp assay as for the MN (data not shown; [16]).
Size-standardized log-THg in yellow perch were compared to water chemistry parameters [ Table S2, plus Cl, Fe, K, Mg, and Mn (data not shown)] by simple regressions (general linear model, GLM) across all lakes sampled in 1996/97 or in 2006/07 (using pooled data).
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We did not find any AIS expression of Nav1.2 in MNs (data not shown).
The pathological features also disclosed no difference between the MN grade, percentage of glomerulosclerosis, tubulointerstitial fibrosis score, or fibrointimal atherosclerosis score between the two genotypes in MN patients (data not shown).
Also Mn TBAB failed to enhance measured fluorescence intensity of supernatants of EA.hy 926 cells and HUVECs after PMA (2 nM, 20 h) stimulation compared to controls without Mn TBAP (data not shown).
Although Cdc6 protein levels are strongly depleted in cdc6-mn mutants (data not shown), low levels of DNA replication were observed in this strain.
In contrast to DPPC monolayers, no LE to LC phase transition could be observed for pure Re-LPS monolayers at relevant lateral pressures (7 30 mN/m) (data not shown).
We observe that ethidium bromide treatment causes a significant (p < 0.01) reduction in K (39%) and Mn (11%) (data not shown) partially mimicking the ionomic phenotypes of the CLUSTER_2 and 12, supporting the association of this ionomic phenotype with a disruption in mitochondrial function.
However, incubation of SN-L11 cocultures or L7-SN-L11 cocultures with netrin-1 did not result in the formation of synapse as shown by the absence of an excitatory post-synaptic potential (EPSP) in the L11 MN after SN stimulation (data not shown).
In the presence of TTX (1 µM), bicuculline (10 µM), strychnine (10 µM) and DAMGO (500 nM), bath application of CX614 (20 µM) had no effect on the inter-event interval (3853±1068 ms to 2375±498 ms) or amplitude (−37±6 pA to −35±5 pA) of mini EPSCs in inspiratory XII MNs (n = 5, data not shown).
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