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They observe a more pronounced destabilization by purine-purine MMs compared to our results.
However, we also identified 152 strains from both libraries (145 deletion strains, 7 DAmP strains) that showed some resistance to MMS compared to WT.
A much higher fraction of the DAmP strains with hypomorphic mutations in essential genes demonstrated sensitivity to MMS compared to the deletion strains.
Therefore, many studies have shown the superiority of Mohs micrographic surgery (MMS) compared to wide local excision (WLE) while considering the local control of DFSP [ 10– 13].
The cell-cycle related gene AtCYCD1 1 was down-regulated 1 day after plant exposure to MMS compared to both the zero time point and to wild-type levels (Fig. 6A C).
Although, the overall expression of TrkA in MM biopsies correlates with worst prognosis, phosphorylated TrkA is detected in a considerably smaller fraction of metastatic MMs compared to the primary samples [ 32], suggesting that activation of TrkA signaling might be important for the early onset of the tumor and might undergo down-regulation once the tumor becomes metastatic.
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The modified assay thus developed is simple and quick, and covers a comparatively large sulfate concentration range (0 5 mM) compared to the standard turbidimetric assay.
Radial shortening of <5 mm compared to the contralateral side.
CT5 had a slice thickness of 5 mm compared to 1 mm of CT1.
The residual leg length difference was 10.4 mm, compared to 25.9 mm preoperatively.
The cooling capacity increased by 50.65% at the fin pitch 3.0 mm compared to 1.0 mm.
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