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This article summarizes the current state of knowledge on these hypothetical "MM stem cells".
Results showed that medium intensity pruning to 10.5 mm stem diameter resulted in a mean DOO of 180 mm.
The identification of MM stem cells responsible for the recurrence of MM is of primary importance in designing targeted therapies to definitely cure this disease.
A prospective comparison of 148 hips in 139 consecutive patients treated with an off-the-shelf uncemented metaphyseal engaging (91 105 mm) stem and 69 hips in 61 patients treated with a custom uncemented metaphyseal engaging short stem was conducted to evaluate the mid-term clinical and radiographic results of an off-the-shelf metaphyseal-engaging short stem implant.
While unsuitable for human cell sorting, SIX2 staining highlights the location of the desired putative MM stem cells.
As a proof-of-principle we chose to analyze sorted NCAM+EpCAM−, NCAM+EpCAM+ (containing putative MM stem- and MM-derived progenitor cells, respectively) in comparison with NCAM− HFK cell populations as NCAM and EpCAM are important surface markers for our characterization system.
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The threshold for acceptable migration of shape-closed designs was defined at 0.15 mm; stems subsiding less than 0.15 mm in 2 years had revision rates of less than 5% at 10 years, while stems exceeding 0.15 mm subsidence had revision rates of more than 5%.
All tibial components had a cemented 35-mm stem extension, and 26 femoral components had a 100-mm uncemented stem extension.
Sulaiman ([2006]) examined the effect of 600-mm stem cutting diameters and planting depths of clones of willow and poplar on tree establishment and biomass production from an alluvial, though finer grained more compact soil.
In Case 38, a PH type 1 with an 11-mm stem diameter was changed to the slightly thicker PH type 2 with a 12-mm stem diameter.
Our study supports the use of the cemented shorter 130-mm stem in older patients especially.
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