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ALS: Amyotrophic Lateral Sclerosis; ME: module eigengene; MM: module membership measure; SOD1: superoxide dismutase-1; WGCNA: weighted gene co-expression network analysis.
WGCNA: weighted gene co-expression network analysis; CD: cluster of differentiation; ME: module eigengene; MM: module membership; KME: eigengene-based connectivity.
AECG: American-European Consensus Group; basebase pair; EULAR: European League against Rheumatism; GO: gene ontology; H & E: hematoxylin and eosin; IL: interleukin; MM: module membership; PCR: polymerase chain reaction; pSS: primary Sjögren's syndrome; TNF: tumor necrosis factor; WGCNA: weighted gene co-expression network analysis.
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For each experiment, MM modules were simulated by independently drawing two genes at random such that all genes were equally likely to be selected.
A modular test chip comprising an array of 2 mm square modules has been designed and fabricated.
After thoroughly mixing the dry ingredients and fish oil with 30%-filtered tap water, experimental diets were pelleted with a laboratory pelleting machine without heating, using a 2-mm diameter module (MK-NG 1500 WSL food grinder).
The resultant mixture was pelleted with a laboratory pelleting machine without heating using a 2-mm diameter module (Baokyong Commercial Co., Busan, Republic of Korea) and air dried for 3 days.
Hence, we used the energy decomposition method within the MM-GBSA module in AMBER11 to analyze how the active site residues stabilize and destabilize the reactive species.
Therefore, in this study, binding free energies were calculated using the MM-GBSA module in AMBER11 complemented by the charge parameters for the noncanonical amino acids introduced in this work.
Open image in new window Fig. 1 Experimental setup Table 1 The parameters of the hobbing process (from FUTU1) Tool Module (mm) Outside diameter (mm) Rake angle Depth of cut (mm) Feed rate (mm) Spindle speed (mpm) DTR-DIN-AA-TIN 1.75 60 0 4375 1.75 200–300.
Mood Module (MM): The MM is a focused interview, that follows DSM-IV criteria [36], for screening medical patients for current depression, composed of simple "yes" and "no" questions.
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