The ~3.8 mm depth range achieved with our present instrumentation enables the in-vitro analysis of small animal bones, for example, mouse bones.
In some oral tissues, for example the ventral tongue, the submucosa is also located within this 1.5 mm depth range and can thus be visualized.
Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 μm axial resolution, 8 μm lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated.
used in this study was 1.35 m long, had an outer diameter of 0.9 mm, a 4.83 mm imaging depth range, and specified axial and transverse resolutions of 20 µm and 25-60 µm, respectively.
The measured sensitivity of the system is 103 dB with 11 μm axial resolution in air (8 μm in tissue) and 2.3 mm imaging depth range in air (1.7 mm in tissue).
The system can support 960 frames per second with 480 kHz axial line rate, 11 μm axial resolution, 20 μm transverse resolution and 2.3 mm imaging depth range in air, corresponding to 8 μm axial resolution, 23 μm transverse resolution and 1.7 mm imaging depth range in tissue.
The system can support 400 frames per second with 1 MHz axial line rate, 11 μm axial resolution, 7 μm transverse resolution and 1.65 mm imaging depth range in air, corresponding to 8 μm axial resolution, 8 μm transverse resolution and 1.2 mm imaging depth range in tissue.
The difference of 50 mm, a depth range often found within a single track had a statistically significant effect on the peak load and the secondary phase loading rate experienced by a horse, particularly under the outlying moisture content conditions (relatively dry or moisture saturated).
In their setup, the A-scan rate was limited by the 46 kHz speed of the line-scan camera, and a 6 dB roll-off of the point spread function was observed at about 0.7 mm, while the depth range was only 1 mm.
For the 4 kHz probe, the beam diameter at the output of the CLS was about 8 mm, the transverse resolution at the focal point was 15 μm, the confocal parameter was 260 μm, and the beam diameter at the position apart from the focal point by 2 mm, (half the depth range), was 230 μm.
Modern cage designs reflect these dimensions, with lateral widths ranging between 12-20 mm and depths ranging between 12-16 mm [ 34].
